Introduction

In recent years, advancements in reproductive medicine have transformed the world of assisted reproduction. One such breakthrough is the genetic testing of embryos before transferring to the womb. 

 Pre-Implantation Genetic Testing (PGT), specifically for aneuploidy,  can play a vital role in improving the success rates of In Vitro Fertilisation (IVF), especially for women over the age of 35.

 

Understanding IVF (In Vitro Fertilisation)

IVF is a medical procedure designed to assist couples who struggle to conceive. IVF can help overcome a wide range of issues that obstruct natural conception.  It involves fertilising the egg and sperm in a laboratory and then transferring the fertilised embryo into the woman’s womb.

Challenges in IVF

While IVF offers hope for many, it is not without its challenges. One of the primary reasons for IVF failure, especially in women over the age of 35 is chromosomal abnormalities in the embryos. 

These abnormalities, known as aneuploidy, can lead to failed implantation or miscarriages. This is where Pre-Implantation Genetic Testing (PGT) of embryos comes into play.

What is PGT for Aneuploidy (PGT-A)?

PGT is a cutting-edge technique that allows embryologists to screen embryos for chromosomal abnormalities before they are implanted into the womb. Aneuploidy refers to an abnormal number of chromosomes in an embryo. PGT for Aneuploidy (PGT-A) identifies these abnormalities, helping embryologists to select the embryos without chromosomal issues for implantation. Beacon CARE Fertility are proud to have had the first PGT-A baby born in Ireland in 2015.

Benefits of Embryo Genetic Testing

  • Improved Pregnancy Rates: By selecting healthy embryos, the chances of successful implantation and a full-term pregnancy are significantly enhanced.
  • Reduced Miscarriage Risk: PGT lowers the risk of miscarriage by avoiding the transfer of embryos with chromosomal abnormalities.
  • Enhanced Family Planning: PGT helps couples understand the genetic health of their embryos, allowing them to make informed decisions about family planning.
  • Cost-Effective: While PGT is an additional procedure, it can ultimately reduce the overall cost of IVF by reducing the need for unnecessary transfer procedures. 

 

Embryo Genetic Testing & Success Rates

A recent American study found that women undergoing IVF achieved a 95% pregnancy success rate over the course of three consecutive frozen embryo transfers, when Embryo Genetic Testing (PGT-A) was utilised.

Over 4000 women with a median age of 35.4 years took part in the retrospective study from the RMA clinic in New Jersey, as reported by the European Society of Human.

You can view Beacon CARE Fertility’s exceptional PGT-A Success Rates below. Full details are on our webpage HERE.

Is PGT Right for You?

PGT is not a one-size-fits-all solution. It is typically recommended for couples with a history of multiple IVF failures, recurrent miscarriages, or women over the age of 35. The decision to undergo PGT should be made after consulting with your Fertility Consultant.

Beacon CARE Fertility & Embryo Genetic Testing:

Beacon CARE Fertility is a world-leading Clinic for Chromosome and Reproductive Genetic Testing. Our vastly experienced Embryology Team has performed thousands of tests since 2013 when we first offered the service.

We also are incredibly proud to have had the first PGT-A baby born in Ireland in 2015. Our Successful Embryo Biopsy Rate is an outstanding *98.7%, positioning ourselves among the top percentile of clinics worldwide for successful biopsy rates.

*Source: Cooper Surgical Genomics, January 1, 2021-May 30, 2022)